Highly Designable Protein Structures and Inter Monomer Interactions

Дата и время публикации : 1997-10-02T17:12:36Z

Авторы публикации и институты :
M. R. Ejtehadi
N. Hamedani
H. Seyed-Allaei
V. Shahrezaei
M. Yahyanejad

Ссылка на журнал-издание: J. Phys. A: Math. Gen. 31 (1998) 6141-6155
Коментарии к cтатье: 14 pages, Latex file, 3 latex and 6 eps figures are included
Первичная категория: cond-mat.soft

Все категории : cond-mat.soft, q-bio

Краткий обзор статьи: By exact computer enumeration and combinatorial methods, we have calculated the designability of proteins in a simple lattice H-P model for the protein folding problem. We show that if the strength of the non-additive part of the interaction potential becomes larger than a critical value, the degree of designability of structures will depend on the parameters of potential. We also show that the existence of a unique ground state is highly sensitive to mutation in certain sites.

Category: Physics